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PubMed: 7514173

Title
Glycogen synthase kinase-3 beta is a dual specificity kinase differentially regulated by tyrosine and serine/threonine phosphorylation.
Journal
The Journal of biological chemistry
Volume
269
Issue
None
Pages
14566-74
Date
1994-05-20
Authors
DePaoli-Roach AA | Fiol CJ | Roach PJ | Wang QM

Evidence 81a73b6c64
JSON

Vm (nM/min/mg) is 2400, 80, 106, 650, and 140; Km is 200, 59, 114, 16 (all uM) and 5mg/ml for phospho-CREB peptide, myelin basic protein, k-casein, phosphatase Inhibitor-2 and phosvitin

a(CHEBI:"calcium dichloride") decreases act(p(HGNC:GSK3B), ma(kin)) View Subject | View Object

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a(CHEBI:"diethyl pyrocarbonate") decreases act(p(HGNC:GSK3B), ma(kin)) View Subject | View Object

Appears in Networks:

a(CHEBI:"glycerol 2-phosphate") decreases act(p(HGNC:GSK3B), ma(kin)) View Subject | View Object

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a(CHEBI:"manganese(II) chloride") decreases act(p(HGNC:GSK3B), ma(kin)) View Subject | View Object

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a(CHEBI:"poly(lysine) polymer") decreases act(p(HGNC:GSK3B), ma(kin)) View Subject | View Object

Appears in Networks:

a(CHEBI:"pyridoxal 5'-phosphate") decreases act(p(HGNC:GSK3B), ma(kin)) View Subject | View Object

Appears in Networks:

a(CHEBI:"sodium chloride") decreases act(p(HGNC:GSK3B), ma(kin)) View Subject | View Object

Appears in Networks:

a(CHEBI:"sodium fluoride") decreases act(p(HGNC:GSK3B), ma(kin)) View Subject | View Object

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a(CHEBI:Phenylglyoxal) decreases act(p(HGNC:GSK3B), ma(kin)) View Subject | View Object

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act(p(HGNC:GSK3B), ma(kin)) increases p(FPLX:CREB, pmod(Ph)) View Subject | View Object

Appears in Networks:

act(p(HGNC:GSK3B), ma(kin)) increases p(HGNC:MBP, pmod(Ph)) View Subject | View Object

Appears in Networks:

act(p(HGNC:GSK3B), ma(kin)) increases p(HGNC:CSN3, pmod(Ph)) View Subject | View Object

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act(p(HGNC:GSK3B), ma(kin)) increases p(HGNC:PPP1R2, pmod(Ph)) View Subject | View Object

Appears in Networks:

act(p(HGNC:GSK3B), ma(kin)) increases p(HGNC:CSNK2B, pmod(Ph)) View Subject | View Object

Appears in Networks:

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If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.