Title

Peroxynitrite-induced nitrative and oxidative modifications alter tau filament formation.

Journal

Biochemistry

Volume

50

Issue

None

Pages

1203-12

Date

2011-02-22

Authors

Binder LI | Hakala K | Kanaan NM | Vana L | Weintraub ST

PN-treated wild-type tau and 5XY→F tau consistently displayed lysine formylation throughout tau in a non-sequence specific distribution. Lysine formylation likely results from reactive free radical exposure caused by PN treatment.

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