Title

Inhibition of neuronal cyclin-dependent kinase-5 by staurosporine and purine analogs is independent of activation by Munc-18.

Journal

Neurochemical research

Volume

21

Issue

None

Pages

629-36

Date

1996-05-01

Authors

Albers RW | Amin N | Grant P | Pant HC | Shetty KT | Veeranna

The kinase activity was inhibited by staurosporine, isopentanyladenine and olomoucine in a dose dependent manner. Kinetic studies indicated Ki values of 39 nM, 38 microM and 8 microM, respectively for staurosporine, isopentanyladenine and olomoucine.

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