Title

Biphenyl-4-yl-acrylohydroxamic acids: Identification of a novel indolyl-substituted HDAC inhibitor with antitumor activity.

Journal

European journal of medicinal chemistry

Volume

112

Issue

None

Pages

99-105

Date

2016-04-13

Authors

Cincinelli R | Cuendet M | Dallavalle S | De Cesare M | Giannini G | Musso L | Nurisso A | Simoes-Pires C | Zuco V | Zunino F | Zwick V

Modification of the cap group of biphenylacrylohydroxamic acid-based HDAC inhibitors led to the identification of a new derivative (3) characterized by an indolyl-substituted 4-phenylcinnamic skeleton.

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