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PubMed: 28540658

Title
Overexpression of the DYRK1A Gene (Dual-Specificity Tyrosine Phosphorylation-Regulated Kinase 1A) Induces Alterations of the Serotoninergic and Dopaminergic Processing in Murine Brain Tissues.
Journal
Molecular neurobiology
Volume
55
Issue
None
Pages
3822-3831
Date
2018-05-01
Authors
Assayag E | Bui LC | Dairou J | Daubigney F | Delabar JM | Janel N | London J | Luquet S | Magnan C | Medjaoui H | Rouch C | Souchet B

Evidence d750486fda
JSON

DYRK1A overexpression induced dramatic deficits in the serotonin contents of the four brain areas tested and major deficits in dopamine and adrenaline contents especially in the hypothalamus.

p(MGI:Dyrk1a) decreases a(CHEBI:serotonin) View Subject | View Object

Appears in Networks:
Annotations
Uberon
dorsal plus ventral thalamus
Uberon
hippocampal formation
Uberon
hypothalamus
Uberon
striatum

p(MGI:Dyrk1a) decreases a(CHEBI:dopamine) View Subject | View Object

Appears in Networks:
Annotations
Uberon
hypothalamus

p(MGI:Dyrk1a) decreases a(CHEBI:adrenaline) View Subject | View Object

Appears in Networks:
Annotations
Uberon
hypothalamus

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