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PubMed: 24033439

Title
Phosphorylation of tau protein at sites Ser(396-404) is one of the earliest events in Alzheimer's disease and Down syndrome.
Journal
Neuropathology and applied neurobiology
Volume
40
Issue
None
Pages
121-35
Date
2014-02-01
Authors
Acevedo-Aquino MC | Luna-Muñoz J | Mondragón-Rodríguez S | Perry G | Williams S

Evidence 196c261593
JSON

Finally, these data validate PHF-1 as an efficient marker for AD cytopathology following the progression of tau aggregation into NFT.

p(HBP:"Tau epitope, PHF1") biomarkerFor path(MESH:"Alzheimer Disease") View Subject | View Object

Appears in Networks:

p(HBP:"Tau epitope, PHF1") increases a(GO:"neurofibrillary tangle") View Subject | View Object

Appears in Networks:

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If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.