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PubMed: 27607061

Title
Tau Tubulin Kinase TTBK2 Sensitivity of Glutamate Receptor GluK2.
Journal
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology
Volume
39
Issue
None
Pages
1444-52
Date
2016-01-01
Authors
Lang F | Matschke V | Meuth SG | Nieding K | Seebohm G | Strutz-Seebohm N

Evidence 85eb7bb1f7
JSON

TTBK2 down-regulates GluK2 activity by decreasing the receptor protein abundance in the cell membrane via RAB5-dependent endocytosis, an effect that may protect against neuroexcitotoxicity.

surf(p(HGNC:GRIK2)) negativeCorrelation act(p(HGNC:RAB5A)) View Subject | View Object

Appears in Networks:

act(p(HGNC:RAB5A)) negativeCorrelation surf(p(HGNC:GRIK2)) View Subject | View Object

Appears in Networks:

p(HGNC:TTBK2) decreases surf(p(HGNC:GRIK2)) View Subject | View Object

Appears in Networks:

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