p(HGNC:PTPA) negativeCorrelation path(MESH:"Alzheimer Disease")

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PubMed:24653673

Decreased expression levels of PTPA in AD brain tissue may also lead to inactivation of PP2A by indirectly increasing levels of PP2A phosphorylated at the Tyr-307 site (Luo et al.,2013).

Related Edges 5

• act(complex(GO:"protein phosphatase type 2A complex")) negativeCorrelation p(FPLX:PPP2, pmod(Ph, Tyr, 307))
• p(HGNC:PTPA) increases act(complex(GO:"protein phosphatase type 2A complex"))
• p(HGNC:PTPA) decreases p(FPLX:PPP2, pmod(Ph, Tyr, 307))
• p(FPLX:PPP2, pmod(Ph, Tyr, 307)) negativeCorrelation act(complex(GO:"protein phosphatase type 2A complex"))
• path(MESH:"Alzheimer Disease") negativeCorrelation p(HGNC:PTPA)

MeSH

Alzheimer Disease

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