g(HBP:"APOE e4") increases bp(GO:"apoptotic process")
ApoE epsilon4 that trafficks to lysosomes more readily than ApoE epsilon3, promotes leakage of acid hydrolases, and induces apoptosis in cultured neuronal cells by forming membrane-damaging intermediates in the low-pHenvironment (Ji et al. 2002).
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If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.