a(HBP:"paired helical filaments") association p(HGNC:MAPT)

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PubMed:22908190

This protein reactive with the initial anti-PHF sera was soon identified as tau, a microtubule-associated protein (MAP), based on its molecular weight, isoform change during development, microtubule- binding activity, and heat stability (Kosik et al. 1986; Nukina and Ihara 1986; see also Brion et al. 1985; Grundke-Iqbal et al. 1986; Wood et al. 1986; discovery of tau in PHF is reviewed in Mandelkow and Mandelkow 2011).

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• p(HGNC:MAPT) association a(HBP:"paired helical filaments")

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