p(HGNC:SQSTM1) increases bp(GO:autophagy)

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PubMed:22908190

For example, p62, an adaptor protein for autophagy, also influences proteasomal degradation, whereas VCP/p97 acting through p62 and ubiquitin regulates both the proteasome-dependent endoplasmic reticulum–associated degradation (ERAD) pathway and aspects of autophagosome maturation (Tresse et al. 2010).

Related Edges 5

• bp(GO:"proteasomal protein catabolic process") association p(HGNC:SQSTM1)
• composite(a(MESH:Ubiquitin), p(HGNC:SQSTM1)) increases act(p(HGNC:VCP))
• p(HGNC:SQSTM1) association bp(GO:"proteasomal protein catabolic process")
• act(p(HGNC:VCP)) regulates bp(GO:"ERAD pathway")
• act(p(HGNC:VCP)) regulates a(GO:autophagosome)

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