p(MGI:Mapt, var("p.Ala152Thr")) increases bp(GO:macroautophagy)

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PubMed:29024336

We found that abundance of autophagic vacuoles (autophagosomes + autolysosomes) significantly increased in cells expressing either of the two tau mutants (Fig. 4d,e). This increase was mainly due to higher content of autolysosomes (red puncta) (Fig. 4d,e), in support of increased macroautophagic flux

Related Edges 5

• p(MGI:Mapt, var("p.Ala152Thr")) increases a(GO:autophagosome)
• p(MGI:Mapt, var("p.Ala152Thr")) increases a(GO:autolysosome)
• p(MGI:Mapt, var("p.Pro301Leu")) increases a(GO:autophagosome)
• p(MGI:Mapt, var("p.Pro301Leu")) increases a(GO:autolysosome)
• p(MGI:Mapt, var("p.Pro301Leu")) increases bp(GO:macroautophagy)

MeSH

Multivesicular Bodies

Confidence

High

MeSH

Brain

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If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.

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