a(CHEBI:nicotine) increases p(HBP:"alpha-4 beta-2 nAChR")

PubMed:19126755

transfection of cells with the beta4 and alpha2 nAChR subunits or expression of these in Xenopus oocytes leads to high-affinity nicotine-binding receptors that upregulate in response to prolonged exposure to nicotine (113, 184, 215).

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