a(CHEBI:"iron coordination entity") positiveCorrelation a(MESH:Cytokines)

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PubMed:25307023

Furthermore, cytokine secretion depends on the coordinated iron in the porphyrin ring (Figueiredo et al, 2007), and nuclear factor-jB (NF-jB), MAPKs activation and ROS are essential for the increase in cytokine production induced by haem (Fernandez et al, 2010).

Related Edges 5

• a(MESH:"Reactive Oxygen Species") positiveCorrelation a(MESH:Cytokines)
• a(MESH:Cytokines) positiveCorrelation a(CHEBI:"iron coordination entity")
• a(MESH:Cytokines) positiveCorrelation a(MESH:"Reactive Oxygen Species")
• p(HGNC:MAPK1) increases a(MESH:Cytokines)
• p(HGNC:NFKB1) increases a(MESH:Cytokines)

Cell Ontology (CL)

macrophage

MeSH

Plasma

MeSH

Urine

MeSH

Anemia, Hemolytic, Autoimmune

Text Location

Review

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If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.

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