p(HGNC:ATG5) decreases path(HBP:Neurodegeneration)

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PubMed:18930136

As mentioned above, dramatic illustration of the interrelatedness of the UPS and autophagy was provided by characterizations of mice with conditional knockout of the essential autophagy genes Atg5 or Atg7 in the central nervous system, which resulted in neurodegeneration with accumulation of ubiquitin-positive pathology [36,37].

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• p(HGNC:ATG7) decreases path(HBP:Neurodegeneration)

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