Appears in Networks 1

Heme Curation v0.0.1-dev

Mechanistic knowledge surrounding heme

Provenance

PubMed:27798618

We focused on macrophage effector functions and found that heme pretreatment (15 min, 3–30 μM unless otherwise indicated) led to a strong, dose-dependent reduction of phagocytosis of E. coli by RAW264.7 macrophages compared with DMSO-treated controls (Fig. 3a,b and Supplementary Fig. 2a).

Related Edges 1

Annotations 4

Cell Ontology (CL)
macrophage
MeSH
Blood
MeSH
Sepsis
Text Location
Results

About

BEL Commons is developed and maintained in an academic capacity by Charles Tapley Hoyt and Daniel Domingo-Fernández at the Fraunhofer SCAI Department of Bioinformatics with support from the IMI project, AETIONOMY. It is built on top of PyBEL, an open source project. Please feel free to contact us here to give us feedback or report any issues. Also, see our Publishing Notes and Data Protection information.

If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.