path(MESH:"Alzheimer Disease") decreases act(complex(p(HGNC:CHRNA4), p(HGNC:CHRNB2)))

PubMed:19293145

Binding studies using subtypeselective labeled ligands suggest that alpha4beta2 receptors are lost in brains from patients with AD (Warpman and Nordberg, 1995; Martin-Ruiz et al., 1999). Regions showing reduced binding levels include the frontal lobe and the temporal cortex (Lai et al., 2006).

MeSH

Brain

MeSH

Frontal Lobe

MeSH

Temporal Lobe

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