a(CHEBI:rosiglitazone) decreases a(CHEBI:"amyloid-beta polypeptide 42")

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PubMed:21718217

Pedersen and Flynn examined the effects of rosiglitazone and found that activation of PPAR-g ameliorated behavioral deficits in the Tg2576 AD mouse model. However, these animals displayed no changes in plaque pathology, but had reduced brain Ab42 levels.

Related Edges 3

• a(CHEBI:rosiglitazone) increases act(p(HGNC:PPARG))
• a(CHEBI:rosiglitazone) increases bp(GO:behavior)
• a(CHEBI:rosiglitazone) causesNoChange a(HBP:HBP00018)

Confidence

High

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