tloc(p(FPLX:NFkappaB), fromLoc(MESH:Cytosol), toLoc(MESH:"Cell Nucleus")) increases bp(GO:"inflammatory response")

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PubMed:29179999

ROS activate various downstream signaling molecules, such as PKC and mitogen-activated protein kinases (MAPKs) that induce nuclear translocation of NF-B and the expression of pro-inflammatory genes [41].

Related Edges 3

• a(CHEBI:"reactive oxygen species") increases act(p(FPLX:PKC))
• a(CHEBI:"reactive oxygen species") increases act(p(FPLX:ERK))
• a(CHEBI:"reactive oxygen species") increases tloc(p(FPLX:NFkappaB), fromLoc(MESH:Cytosol), toLoc(MESH:"Cell Nucleus"))

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