p(HGNC:PPP2CA) negativeCorrelation path(MESH:"Alzheimer Disease")

View Subject View Object

PubMed:24653673

Deficits in PP2A activity are in line with the reported down-regulation of PP2A catalytic C subunit at the gene (Loring et al.,2001), mRNA (Vogelsberg-Ragaglia et al.,2001) and protein (Sontag et al.,2004b) expression levels in AD.

Related Edges 15

• act(complex(GO:"protein phosphatase type 2A complex")) association p(HGNC:PPP2CB)
• act(complex(GO:"protein phosphatase type 2A complex")) association p(HGNC:PPP2CA)
• p(HGNC:PPP2CA) association act(complex(GO:"protein phosphatase type 2A complex"))
• p(HGNC:PPP2CB) association act(complex(GO:"protein phosphatase type 2A complex"))
• p(HGNC:PPP2CB) negativeCorrelation path(MESH:"Alzheimer Disease")
• g(HGNC:PPP2CA) negativeCorrelation path(MESH:"Alzheimer Disease")
• g(HGNC:PPP2CB) negativeCorrelation path(MESH:"Alzheimer Disease")
• path(MESH:"Alzheimer Disease") negativeCorrelation g(HGNC:PPP2CA)
• path(MESH:"Alzheimer Disease") negativeCorrelation r(HGNC:PPP2CA)
• path(MESH:"Alzheimer Disease") negativeCorrelation p(HGNC:PPP2CA)
• path(MESH:"Alzheimer Disease") negativeCorrelation g(HGNC:PPP2CB)
• path(MESH:"Alzheimer Disease") negativeCorrelation r(HGNC:PPP2CB)
• path(MESH:"Alzheimer Disease") negativeCorrelation p(HGNC:PPP2CB)
• r(HGNC:PPP2CA) negativeCorrelation path(MESH:"Alzheimer Disease")
• r(HGNC:PPP2CB) negativeCorrelation path(MESH:"Alzheimer Disease")

BEL Commons is developed and maintained in an academic capacity by Charles Tapley Hoyt and Daniel Domingo-Fernández at the Fraunhofer SCAI Department of Bioinformatics with support from the IMI project, AETIONOMY. It is built on top of PyBEL, an open source project. Please feel free to contact us here to give us feedback or report any issues. Also, see our Publishing Notes and Data Protection information.

If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.

---