a(MESH:VU0357017) increases bp(GO:"behavioral fear response")

PubMed:24511233

More recently, the M1-selective allosteric agonist VU0357017 was discovered, which displayed improved potency via binding to a novel allosteric site on the M1 mAChR. VU0357017 significantly blocked scopolamine-impaired contextual fear conditioning and enhanced spatial and contextual fear learning

Related Edges 3

• a(MESH:VU0357017) increases complex(a(MESH:VU0357017), p(HGNC:CHRM1))
• a(MESH:VU0357017) decreases act(a(CHEBI:scopolamine))
• complex(a(MESH:VU0357017), p(HGNC:CHRM1)) increases act(p(HGNC:CHRM1))

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