a(CHEBI:Anatabine) decreases act(complex(GO:"NF-kappaB complex"))

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PubMed:21958873

In addition, an inhibition of p65 NFκB phosphorylation was observed following treatment with anatabine in 7W CHO overexpressing APP (Fig. 6A), in HEK293 (Fig. 6B) and in human neuronal like SH-SY5Y cells (Fig. 6C) showing that anatabine can prevent NFκB activation in various cell lines.

Related Edges 1

• a(CHEBI:Anatabine) decreases p(HGNC:RELA, pmod(Ph))

Experimental Factor Ontology (EFO)

CHO cell

Experimental Factor Ontology (EFO)

SH-SY5Y

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