p(HGNC:TFEB) decreases path(MESH:"Plaque, Amyloid")

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PubMed:29626319

Xiao et al. have also obtained the consistent conclusion that transcriptional factor EB, a master regulator of lysosome biogenesis, improves lysosomal function in astrocytes, which may promote Aβ clearance and attenuate plaque pathogenesis (Xiao et al. 2014)

Related Edges 2

• p(HGNC:TFEB) increases deg(a(CHEBI:"amyloid-beta"))
• p(HGNC:TFEB) increases act(a(GO:lysosome))

MeSH

Astrocytes

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