bp(GO:"platelet activation") positiveCorrelation path(HP:"Paroxysmal nocturnal hemoglobinuria")

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PubMed:29929138

The average mean fluorescence (MF) for CD61 staining of was slightly reduced in patients with primary Cys89Tyr CD59 deficiency and PNH as compared to controls. However, the average MF for CD62P expression in the healthy individuals was 38.3 ± 3.1 compared to 48.5 ± 4.7 in patients with primary Cys89Tyr CD59 deficiency (p < 0.0085) and 54.0 ± 4.2 in patients with PNH (p < 0.0013), indicating a significantly more activated platelet phenotype in both the patients with PNH and those with primary Cys89Tyr CD59 deficiency.

Related Edges 2

• p(HGNC:CD59, var("p.Cys89Tyr")) increases bp(GO:"platelet activation")
• path(HP:"Paroxysmal nocturnal hemoglobinuria") positiveCorrelation bp(GO:"platelet activation")

Cell Ontology (CL)

erythrocyte

Cell Ontology (CL)

neutrophil

Cell Ontology (CL)

platelet

MeSH

Hemoglobinuria, Paroxysmal

Text Location

Results

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