p(HGNC:TGFB1) biomarkerFor path(MESH:"Alzheimer Disease")

View Subject View Object

PubMed:26304819

Aβ 42 in the medium decreased in a GA dose-dependent manner (Fig. 3a). In contrast, GA significantly increased tau and its phosphorylated form, p-tauT181 (Fig. 3b,c) in the medium. In addition, VEGF (Fig. 3e) and TGF-β (Fig. 3f), which are also AD biomarkers, were increased when the concentration of GA added was greater than 0.7 mM.

Related Edges 6

• a(CHEBI:glyceraldehyde) decreases p(HGNC:APP, frag("672_713"))
• a(CHEBI:glyceraldehyde) increases p(HGNC:MAPT)
• a(CHEBI:glyceraldehyde) increases p(HGNC:MAPT, pmod(Ph, Thr, 181))
• a(CHEBI:glyceraldehyde) increases p(HGNC:VEGFA)
• a(CHEBI:glyceraldehyde) increases p(HGNC:TGFB1)
• p(HGNC:VEGFA) biomarkerFor path(MESH:"Alzheimer Disease")

BEL Commons is developed and maintained in an academic capacity by Charles Tapley Hoyt and Daniel Domingo-Fernández at the Fraunhofer SCAI Department of Bioinformatics with support from the IMI project, AETIONOMY. It is built on top of PyBEL, an open source project. Please feel free to contact us here to give us feedback or report any issues. Also, see our Publishing Notes and Data Protection information.

If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.

---