bp(GO:"synaptic transmission, cholinergic") association a(CHEBI:"amyloid-beta")

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PubMed:19293145

Consequently, there is mounting evidence that Abeta affects cholinergic signaling independent of its cytotoxic action. For example, Abeta blocks long-term potentiation, a cellular correlate of learning, through activation of JNK and p38MAPK (Wang et al., 2004).

Related Edges 4

• a(CHEBI:"amyloid-beta") association bp(GO:"synaptic transmission, cholinergic")
• a(CHEBI:"amyloid-beta") increases act(p(HGNC:MAPK8))
• a(CHEBI:"amyloid-beta") increases act(p(HGNC:MAPK14))
• composite(p(HGNC:MAPK14), p(HGNC:MAPK8)) decreases bp(GO:"long-term synaptic potentiation")

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