a(CHEBI:codeine) increases act(p(HGNCGENEFAMILY:"Cholinergic receptors nicotinic subunits"))

PubMed:19126755

For instance, studies carried out in PC12 cells demonstrated that codeine, a drug with no significant effect on ChE, can activate nicotinic single-channel currents and that this nicotinic agonist effect is sensitive to inhibition by FK1 while unaffected by classical nAChR antagonists (450).

Related Edges 2

• a(CHEBI:codeine) causesNoChange a(MESH:Cholinesterases)
• a(HBP:"FK1 antibody") decreases a(CHEBI:codeine)

MeSH

PC12 Cells

Text Location

Review

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