p(HGNC:PYCARD) increases act(complex(GO:"IPAF inflammasome complex"))

PubMed:24561250

The adaptor protein ASC is important for the activation of NLRC4 inflammasome in astrocytes, while Naip 5 is not (Liu and Chan, 2014)

Cell Ontology (CL)

astrocyte

Confidence

High

NeuroMMSigDB

Caspase subgraph

BEL Commons is developed and maintained in an academic capacity by Charles Tapley Hoyt and Daniel Domingo-Fernández at the Fraunhofer SCAI Department of Bioinformatics with support from the IMI project, AETIONOMY. It is built on top of PyBEL, an open source project. Please feel free to contact us here to give us feedback or report any issues. Also, see our Publishing Notes and Data Protection information.

If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.