a(CHEBI:nicotine) decreases path(MESH:"Colitis, Ulcerative")

PubMed:19126755

Modulation by nicotine of inflammatory responses in the intestines is much better reported. Early studies found that patients with ulcerative colitis who stopped smoking tobacco developed the disease or exhibited more severe disease progression, which was ameliorated by either returning to smoking (58, 401, 466), or, in some cases, administering nicotine through transdermal patches (313).In contrast, patients with Crohn’s disease experience much more severe disease when smoking (401).

Related Edges 3

• act(a(CHEBI:nicotine)) regulates bp(GO:"inflammatory response")
• path(MESH:"Tobacco Use Disorder") decreases path(MESH:"Colitis, Ulcerative")
• path(MESH:"Tobacco Use Disorder") increases path(MESH:"Crohn Disease")

MeSH

Intestines

Text Location

Review

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