path(MESH:"Alzheimer Disease") association a(GO:"neurofibrillary tangle")

View Subject View Object

PubMed:22817713

AD (Alzheimer’s disease) is a progressive neurodegenerative disorder characterized by the extracellular accumulation of senile plaques composed of Aβ (amyloid β-peptide) and the intracellular accumulation of the MAP (microtubuleassociated protein) tau into both non-filamentous and filamentous inclusions, such as NFTs (neurofibrillary tangles), NTs (neuropil threads) and NPs (neuritic plaques) [1,2]

Related Edges 5

• a(GO:"neurofibrillary tangle") association path(MESH:"Alzheimer Disease")
• a(MESH:"Neuropil Threads") association path(MESH:"Alzheimer Disease")
• path(MESH:"Alzheimer Disease") positiveCorrelation path(MESH:"Plaque, Amyloid")
• path(MESH:"Alzheimer Disease") association a(MESH:"Neuropil Threads")
• path(MESH:"Plaque, Amyloid") positiveCorrelation path(MESH:"Alzheimer Disease")

Confidence

Medium

MeSH

Intracellular Space

BEL Commons is developed and maintained in an academic capacity by Charles Tapley Hoyt and Daniel Domingo-Fernández at the Fraunhofer SCAI Department of Bioinformatics with support from the IMI project, AETIONOMY. It is built on top of PyBEL, an open source project. Please feel free to contact us here to give us feedback or report any issues. Also, see our Publishing Notes and Data Protection information.

If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.

---