p(HGNC:HBB) negativeCorrelation bp(GO:"regulation of glucose-6-phosphatase activity")

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PubMed:29956069

Nevertheless, the crosstalk between glucose and heme metabolism in sepsis is bidirectional since an excessive accumulation of cell-free heme following hemolysis influences the glucose metabolism by iron-driven oxidative inhibition of the glucose-6-phosphatase (a liver enzymes being important for endogenous glucose production via gluconeogenesis and glycogenolysis) [14].

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• bp(GO:"regulation of glucose-6-phosphatase activity") negativeCorrelation p(HGNC:HBB)

Cell Ontology (CL)

erythrocyte

MeSH

Liver

MeSH

Sepsis

Text Location

Review

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