p(MGI:Prdx2) negativeCorrelation bp(MESH:"Oxidative Stress")

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PubMed:25264713

Peroxiredoxin-2 (Prx-2) has emerged as the critical antioxidant protecting RBCs from H2O2 produced endogenously (by Hb autoxidation and subsequent superoxide dismutation) and exogenously (e.g., from activated neutrophils) at low (physiologic) concentrations (11, 32, 38, 40, 43, 45) and, therefore, may limit oxidative injury to other cells/tissues in the vasculature (6, 57).

Related Edges 3

• a(CHEBI:"hydrogen peroxide") negativeCorrelation p(MGI:Prdx2)
• bp(MESH:"Oxidative Stress") negativeCorrelation p(MGI:Prdx2)
• p(MGI:Prdx2) negativeCorrelation a(CHEBI:"hydrogen peroxide")

Cell Ontology (CL)

erythrocyte

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