p(UNIPROT:P32589) decreases path(MESH:"Protein Aggregation, Pathological")

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PubMed:27491084

The co- chaperone HSP40 (dHdj-1 and SIS1) and the nucleotide exchange factor SSE1 that specifically modulate HSP70 activity were also shown to suppress toxicity and aggregation in yeast and fly disease models (Chan et al., 2000; Krobitsch and Lindquist, 2000; Sadlish et al., 2008).

Related Edges 2

• p(UNIPROT:P32589) regulates act(p(FPLX:HSPA))
• p(UNIPROT:P32589) decreases path(HBP:proteotoxicity)

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