a(HBP:"paired helical filaments") decreases act(complex(GO:"proteasome complex"))

PubMed:14556719

They present evidence that paired helical filaments obtained from AD brain or generated in vitro can inhibit proteasome function and that in AD brain tissue these filaments coimmunoprecipitate with the proteasome (Keck et al., 2003).

MeSH

Alzheimer Disease

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