act(complex(GO:"proteasome complex")) decreases path(HBP:Neurodegeneration)

PubMed:18930136

There have been fewer efforts to manipulate UPS function for therapeutic benefit in neurodegenerative disease, but it was recently shown that use of a proteasome activator enhanced survival in an in vitro model of Huntington’s disease [58], suggesting that augmenting other routes of protein degradation may also provide neuroprotection.

MeSH

Huntington Disease

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