path(HM:"endothelial lesions") increases path(MESH:Thrombosis)

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PubMed:29956069

During HUS, endothelial lesions cause a complement dependent activation of immune response and local thrombus formation—attachment of fibrin and platelets to the endothelial lesions and consequently disseminated intravascular coagulation (DIC)—and further mechanical destruction of the red blood cells in the fibrin mesh resulting in hemolysis [82].

Related Edges 2

• path(HM:"endothelial lesions") increases path(MESH:Hemolysis)
• path(HM:"endothelial lesions") increases path(MESH:"Disseminated Intravascular Coagulation")

Cell Ontology (CL)

erythrocyte

MeSH

Liver

MeSH

Atypical Hemolytic Uremic Syndrome

Text Location

Review

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