p(HGNC:APOE) increases deg(a(CHEBI:"amyloid-beta"))

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PubMed:21718217

They were able to show that the lipidation of ApoE enhanced the degradation of soluble species of Ab by neprilysin in the endolytic compartments of microglia as well as extracellularly through the actions of the insulindegrading enzyme (IDE) [13].

Related Edges 2

• p(HGNC:IDE) increases deg(a(CHEBI:"amyloid-beta"))
• p(HGNC:MME) increases deg(a(CHEBI:"amyloid-beta"))

Confidence

High

MeSH

Microglia

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