a(CHEBI:nicotine) increases complex(p(FPLX:"PI3K_p85"), p(HGNC:CHRNA7), p(HGNC:FYN))

PubMed:19293145

The neuroprotective activation of the PI3K/AKT pathway by nicotine involves the tyrosine kinase FYN, which physically interacts with alpha7 nAChRs, and the p85 subunit of PI3K in rat fetal cortical neurons in culture (Kihara et al., 2001).

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