a(CHEBI:donepezil) increases p(HGNC:CHRNA4)

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PubMed:19293145

Donepezil, which protects cultured rat cortical neurons, when applied for 4 days resulted in an up-regulation of alpha4 and alpha7 nAChRs with the result that donepezil was even more potently protective (Kume et al., 2005).

Related Edges 2

• a(CHEBI:donepezil) increases p(HGNC:CHRNA7)
• a(CHEBI:donepezil) increases bp(MESH:Neuroprotection)

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