p(HBP:"Tau isoform F (441 aa)", var("p.Arg406Tyr")) decreases p(HGNC:MAPT, pmod(Ph, Thr, 212))

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PubMed:21339331

The quantification of all immunoreactive bands revealed that the R406W mutation exhibits a decreased phosphorylation at T205, T212, and the PHF1 epitope (S396/S404; reductions of 40–65%) as compared with wt tau, whereas other sites were not affected or only slightly affected (T181, S199, S214, and S262).

Related Edges 3

• p(HBP:"Tau isoform F (441 aa)", var("p.Arg406Tyr")) decreases p(HGNC:MAPT, pmod(Ph, Thr, 205))
• p(HBP:"Tau isoform F (441 aa)", var("p.Arg406Tyr")) decreases p(HGNC:MAPT, pmod(Ph, Ser, 396))
• p(HBP:"Tau isoform F (441 aa)", var("p.Arg406Tyr")) decreases p(HGNC:MAPT, pmod(Ph, Ser, 404))

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