p(HGNC:MAPT, pmod(HBP:hyperphosphorylation)) increases path(MESH:"Alzheimer Disease")

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PubMed:29758300

While misfolding of Aβ peptide and hyperphosphorylation of tau are recognized as pathogenic mechanisms of AD, accumulation of α-synuclein, which is recognized more as a risk factor for Parkinson’s disease (PD), also plays a pathological role in AD [29].

Related Edges 4

• p(HGNC:SNCA) positiveCorrelation path(MESH:"Alzheimer Disease")
• p(HGNC:SNCA) increases path(MESH:"Parkinson Disease")
• p(MESH:"Amyloid beta-Peptides", pmod(HBP:misfolding)) increases path(MESH:"Alzheimer Disease")
• path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:SNCA)

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