p(HGNC:PYCARD) association composite(complex(GO:"inflammasome complex"), p(HGNC:NLRP2))

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PubMed:24561250

They include the adaptor protein, ASC (apoptosis-associated speck-like protein containing a caspase recruitment domain), which is an essential component of the NLRP1, NLRP2 and NLRP3 inflammasomes, but not of the more complex NLRC4 inflammasome (Martinon et al., 2009; Minkiewicz et al., 2013; Schroder and Tschopp, 2010)

Related Edges 1

• composite(complex(GO:"inflammasome complex"), p(HGNC:NLRP2)) association p(HGNC:PYCARD)

Confidence

Medium

NeuroMMSigDB

Caspase subgraph

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