m(MIRBASE:"hsa-mir-146a") positiveCorrelation path(MESH:"Alzheimer Disease")

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PubMed:27288790

Elevated miRNA-146a in AD brain has been shown to also specifically target the interleukin-1 associated ki- nase-1 (IRAK-1) mRNAs, it is believed to contribute to altered innate immune responses and neuroinflammation in degenerating human brain cells and tissues in inflammatory neurodegenerative diseases including AD and in primary human brain cells stressed with ROS- generating metal sulfates [69].

Related Edges 6

• bp(GO:"immune response") association m(MIRBASE:"hsa-mir-146a")
• m(MIRBASE:"hsa-mir-146a") association r(HGNC:IRAK1)
• m(MIRBASE:"hsa-mir-146a") association bp(GO:"immune response")
• m(MIRBASE:"hsa-mir-146a") increases path(HP:Neurodegeneration)
• path(MESH:"Alzheimer Disease") positiveCorrelation m(MIRBASE:"hsa-mir-146a")
• r(HGNC:IRAK1) association m(MIRBASE:"hsa-mir-146a")

MeSH

Brain

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