p(HGNC:HBB) increases path(HM:"Endothelial dysfunction")

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PubMed:26475040

Many studies have explored basic mechanisms of Hb or heme triggered endothelial damage and have suggested that oxidative reactions of Hb generate multiple toxic species such as free heme that is released from ferric Hb, iron, free radicals, and globin aggregation products [15],[16],[17],[18],[19],[20],[21],[22],[23],[24],[25].

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• a(CHEBI:heme) increases path(HM:"Endothelial dysfunction")

MeSH

Anemia, Sickle Cell

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Abstract

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