act(p(FPLX:TLR)) increases p(HGNC:IL1B)

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PubMed:23702978

First, a bacterial Toll-like receptor (TLR) activator leads to cellular priming and upregulation of NLRP3 and pro-IL-1β expression (the priming checkpoint in the standard model)37,38.

Related Edges 1

• act(p(FPLX:TLR)) increases p(HGNC:NLRP3)

Confidence

High

NeuroMMSigDB

Interleukin signaling subgraph

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