path(MESH:D000544) decreases bp(GO:"GO:0015871")
Furthermore, synaptic reuptake of choline, which is essential for the synthesis of ACh molecules that are to be released into the synaptic cleft in subsequent rounds of neurotransmission, is reduced to -60% of normal levels in Alzheimer's disease, and direct measurement reveals that levels of ACh synthesis are reduced by one half in affected patients.
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If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.