p(HGNC:LRP1) increases deg(complex(a(CHEBI:heme), p(HGNC:HPX)))

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PubMed:25307023

Normally, haemopexin safely transports haem away from the vessel wall to ligate LRP1 (also termed CD91) on hepatocytes and macrophages, where the haem–haemopexin complex is endocytosed and haem is degraded intracellularly (Hvidberg et al, 2005).

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• p(HGNC:LRP1) increases deg(a(CHEBI:heme))

Cell Ontology (CL)

macrophage

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