complex(p(FPLX:HSP90), p(HGNC:STUB1)) association p(HGNC:AKT1)

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PubMed:21882945

Interestingly, it was recently found that reducing the levels of Akt, another client of the Hsp90/CHIP complex, facilitates tau degradation [123], suggesting a synchronized balance between competing Hsp90 substrates that may be driven, in part, by their relative abundance or susceptibility to Hsp90 binding

Related Edges 3

• deg(p(HGNC:MAPT)) negativeCorrelation p(HGNC:AKT1)
• p(HGNC:AKT1) association complex(p(FPLX:HSP90), p(HGNC:STUB1))
• p(HGNC:AKT1) negativeCorrelation deg(p(HGNC:MAPT))

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