a(CHEBI:rosiglitazone) decreases a(HBP:HBP00018)

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PubMed:21718217

These animals were treated with a low dose of rosiglitazone (3 mg/kg/ day) for 12 weeks and evaluated for plaque deposition and behavior. These animals displayed an approximate 50% decrease in amyloid deposition, a decrease in Ab oligomers, preservation of pre and postsynaptic proteins and the attenuation of cognitive deficits in the Morris water maze.

Related Edges 2

• a(CHEBI:rosiglitazone) decreases a(CHEBI:"amyloid-beta")
• a(CHEBI:rosiglitazone) increases bp(GO:"learning or memory")

Confidence

High

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