p(HBP:"Tau aggregates") positiveCorrelation a(CHEBI:"amyloid-beta")

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PubMed:28500862

In the HEK cell biosensor assay, tau from AD cases with plaques enhanced tau aggregates compared to tau from cases without plaques. In APP/PS1 cross with rTg4510 mice (P301L mutant human tau), tau seeding activity was threefold increased over the rTg4510 strain, without change in tau production or extracellular release.

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• a(CHEBI:"amyloid-beta") positiveCorrelation p(HBP:"Tau aggregates")

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